Bioengineering, Biosystems and Synthetic Biology


Our group focuses on the development of technology platforms based on bioprocesses and synthetic biology that generate new applications, new products and new production systems. Our main research lines are: a) Design of bioprocesses, b) novel technologies for bioseparation, c) technologies for measurement and early detection and d) synthetic biology.

The bioprocess line focuses primarily on the design, implementation and scaling of unique biotechnological processes for products with commercial potential. The objective of the research line of novel technologies for bioseparation is to generate new strategies for recovery and purification that result in new platforms and products (proteins, enzymes, cells, etc.). The development of technologies for early detection involves the design and use of the micro-devices process for the creation of measurement systems. The research line of synthetic biology focuses on generating unique microbial production systems for obtaining high-value products.

Research lines

• Bioprocess design   
• Innovative bioseparation technologies   
• Measurement and early detection technologies   
• Synthetic biology


José Guillermo González Valdez

Core researchers

Cuauhtemoc Licona Cassani
Daniel Alberto Jacobo Velázquez
Jorge Alejandro Benavides Lozano
José Manuel Aguilar Yáñez
Juan Carlos Amador Molina
Karla Patricia Mayolo Deloisa
Marcos de Donato Capote
Oscar Alejandro Aguilar Jiménez
Rodrigo Balam Muñoz Soto


Distinguished researcher

Richard C. Willson - Universidad de Houston


Doctoral students

Ana Mariel Torres Contreras
Edgar Acuña González
Israel Alfonso Ramírez Alanís
Jesús Hernández Pérez
Luis Alberto Mejía Manzano
Marco Arnulfo Mata Gómez
Mario Antonio Torres Acosta
Rebeca García Varela
Soledad Mora Vásquez

Authors Title Publication
Kiss T, Grievink J, Rito-Palomares M. A systems engineering perspective on process integration in biotechnology. Journal of Chemical Technology and Biotechnology. (2015).
Gómez-Loredo A, González-Valdez J, Rito-Palomares M. Insights on the Downstream Purification of Fucoxanthin, a Microalgal Carotenoid, From an Aqueous Two-Phase System Stream Exploiting Ultrafiltration. Journal of Applied Phycology. (2015). In press.
Mata-Gómez M, Heerd D, Oyanguren-García I, Barbero F., Rito-Palomares M. Fernández- Lahore M. Characterization of a novel pectin-degrading enzyme complex from Aspergillus sojae ATCC 20235 mutants. Journal of Science of Food and Agriculture. (2015). In press.
Mayolo-Deloisa K, González-González M, Simental-Martínez J, Rito-Palomares M. Aldehyde PEGylation of laccase from Trametes versicolor in route to increase its stability: Effect on enzymatic activity. Journal of Molecular Recognition. 28, 3, 173–179 (2015).
González-González M, Rito-Palomares M. Application of affinity aqueous two-phase systems for the fractionation of CD133+ stem cells from human umbilical cord blood. Journal of Molecular Recognition. 28, 3, 142-147 (2015).