Dr. Luz María Martínez Calderón graduated with honors from Tecnológico de Monterrey with a Bachelor of Science in Chemistry and obtained her Ph.D. in Chemistry from Arizona State University. She is currently Research Professor at the Department of ​​Chemistry and Nanotechnology at the Tecnológico de Monterrey, Monterrey campus, and participates as an adjunct professor in the Department of Chemistry at Rice University.

Her research lines include: Design and construction of portable instruments for thermal and structural characterization, Preparation and characterization of micro and Nano-dispersions of thermally stable amorphous drugs to improve solubility and bioavailability of poorly soluble active principles, Evaluation of therapeutic efficiency of new pharmaceutical formulations in the form of co-amorphous and co-crystalline formulations with potential applications in the treatment of high incidence diseases (hypertension-hypercholesterolemia-diabetes) and Stabilization and thermal characterization of active principles and biomolecules with applications in the biotechnology and pharmaceutical industry.

In terms of attracting funds and research projects, Dr. Martínez has served as coordinator and head of projects such as "Estudio de las transiciones de fase e interacciones intermoleculares en sistemas binarios en función de su composición y temperatura", funded by the call of Ciencia Básica SEP-CONACyT 2016-2020, "Estudio del mecanismo de preservación de biomoléculas de través de la generación de matrices vítreas de azúcares no reductores", funded by the call of Ciencia Básica SEP-Conacyt-2008, the educational Innovation project "Construyendo nuestros instrumentos de Medición: Construcción y uso de instrumentos de caracterización térmica de materiales. Do it yourself", funded by the NOVUS 2012 call for Educational Innovation and "Optimización de procesos de preservación de biomoléculas", funded by the Zambrano-Hellion Fund.

Dr. Martínez has generated knowledge through the direction of more than 30 undergraduate and graduate thesis projects; her scientific contributions have been published in indexed journals such as Journal of Chemical Education, Thermochimica Acta, Biopolymers, Nature, International Journal of pharmaceutics, Molecules, European Journal of Pharmaceutics and Biopharmaceutics, among others. She has been a member of the steering committee of the Consejo Nacional de la Enseñanza de las Ciencias Químicas A.C. from 2011 to 2017 and is a member of the AAPS (American Association of Pharmaceutical Scientists) and the ACS (American Chemical Society).

She worked in the industrial sector developing analytical techniques to measure physicochemical properties of glass. As a result, she received recognition for her contribution to Technological Development in VITRO.

• Analysis of Properties and Transformation of Matter
• Analysis of the Transformation of Matter in Chemical Processes
• Chemical Research
• Chemistry
• Directed Study
• Doctoral Defense
• Doctoral Research
• Foundation of the Structure and Transformation of Matter
• Guided Research
• Integration Project in Chemistry and Nanotechnology
• Introduction to Chemical Research
• Research Internship
• Research Project in Chemistry and Nanotechnology
• Research Proposal

• Nano and micro dispersions of two-phase amorphous-amorphous drug formulations as strategy to enhance solubility of pharmaceuticals. Materials Today: Proceedings 13, pp. 390-396 (2019)
• Roles of Undergraduate Students: Trainee, Tutor and Designer" International Journal on Interactive Design and Manufacturing (IJIDeM) 13(4), pp. 1457-1467 (2019) 
• "Highly Soluble Glimepiride and Irbesartan Co-amorphous Formulation with Potential Application in Combination Therapy" (AAPS PharmSciTech 20(4),144 1-12 (2019)
• "Co-Amorphous Simvastatin-Nifedipine with Enhanced Solubility for Possible Use in Combination Therapy of Hypertension and Hypercholesterolemia" Molecules, 23, 2161 (2018)
• "Two-phase amorphous-amorphous solid drug dispersion with enhanced stability, solubility and bioavailability; resulting from ultrasonic dispersion of an immiscible system" European Journal of Pharmaceutics and Biopharmaceutics, 119 243-252 (2017) 

More publications

• Doctor of Chemistry, Arizona State University
• Bachelor of Chemical Sciences, Tecnológico de Monterrey

• National Award " Inspiring Profesor", for Research and Graduate (2016 y 2020)
• MUJER-TEC-2013 (Mentoring category)
• Distinguished Novus-Professor (distinction for profile as an innovator in education)
• Excellence in Honors Teaching Award
• Mexican Researcher Certification - Level 1 (Martínez-Calderón, Luz María)

Dr. Luz María Martínez Calderón graduated with honors from Tecnológico de Monterrey with a Bachelor of Science in Chemistry and obtained her Ph.D. in Chemistry from Arizona State University. She is currently Research Professor at the Department of ​​Chemistry and Nanotechnology at the Tecnológico de Monterrey, Monterrey campus, and participates as an adjunct professor in the Department of Chemistry at Rice University.

Her research lines include: Design and construction of portable instruments for thermal and structural characterization, Preparation and characterization of micro and Nano-dispersions of thermally stable amorphous drugs to improve solubility and bioavailability of poorly soluble active principles, Evaluation of therapeutic efficiency of new pharmaceutical formulations in the form of co-amorphous and co-crystalline formulations with potential applications in the treatment of high incidence diseases (hypertension-hypercholesterolemia-diabetes) and Stabilization and thermal characterization of active principles and biomolecules with applications in the biotechnology and pharmaceutical industry.

In terms of attracting funds and research projects, Dr. Martínez has served as coordinator and head of projects such as "Estudio de las transiciones de fase e interacciones intermoleculares en sistemas binarios en función de su composición y temperatura", funded by the call of Ciencia Básica SEP-CONACyT 2016-2020, "Estudio del mecanismo de preservación de biomoléculas de través de la generación de matrices vítreas de azúcares no reductores", funded by the call of Ciencia Básica SEP-Conacyt-2008, the educational Innovation project "Construyendo nuestros instrumentos de Medición: Construcción y uso de instrumentos de caracterización térmica de materiales. Do it yourself", funded by the NOVUS 2012 call for Educational Innovation and "Optimización de procesos de preservación de biomoléculas", funded by the Zambrano-Hellion Fund.

Dr. Martínez has generated knowledge through the direction of more than 30 undergraduate and graduate thesis projects; her scientific contributions have been published in indexed journals such as Journal of Chemical Education, Thermochimica Acta, Biopolymers, Nature, International Journal of pharmaceutics, Molecules, European Journal of Pharmaceutics and Biopharmaceutics, among others. She has been a member of the steering committee of the Consejo Nacional de la Enseñanza de las Ciencias Químicas A.C. from 2011 to 2017 and is a member of the AAPS (American Association of Pharmaceutical Scientists) and the ACS (American Chemical Society).

She worked in the industrial sector developing analytical techniques to measure physicochemical properties of glass. As a result, she received recognition for her contribution to Technological Development in VITRO.

• Analysis of Properties and Transformation of Matter
• Analysis of the Transformation of Matter in Chemical Processes
• Chemical Research
• Chemistry
• Directed Study
• Doctoral Defense
• Doctoral Research
• Foundation of the Structure and Transformation of Matter
• Guided Research
• Integration Project in Chemistry and Nanotechnology
• Introduction to Chemical Research
• Research Internship
• Research Project in Chemistry and Nanotechnology
• Research Proposal

• Nano and micro dispersions of two-phase amorphous-amorphous drug formulations as strategy to enhance solubility of pharmaceuticals. Materials Today: Proceedings 13, pp. 390-396 (2019)
• Roles of Undergraduate Students: Trainee, Tutor and Designer" International Journal on Interactive Design and Manufacturing (IJIDeM) 13(4), pp. 1457-1467 (2019) 
• "Highly Soluble Glimepiride and Irbesartan Co-amorphous Formulation with Potential Application in Combination Therapy" (AAPS PharmSciTech 20(4),144 1-12 (2019)
• "Co-Amorphous Simvastatin-Nifedipine with Enhanced Solubility for Possible Use in Combination Therapy of Hypertension and Hypercholesterolemia" Molecules, 23, 2161 (2018)
• "Two-phase amorphous-amorphous solid drug dispersion with enhanced stability, solubility and bioavailability; resulting from ultrasonic dispersion of an immiscible system" European Journal of Pharmaceutics and Biopharmaceutics, 119 243-252 (2017) 

More publications

• Doctor of Chemistry, Arizona State University
• Bachelor of Chemical Sciences, Tecnológico de Monterrey

• National Award " Inspiring Profesor", for Research and Graduate (2016 y 2020)
• MUJER-TEC-2013 (Mentoring category)
• Distinguished Novus-Professor (distinction for profile as an innovator in education)
• Excellence in Honors Teaching Award
• Mexican Researcher Certification - Level 1 (Martínez-Calderón, Luz María)

"It is difficult to remain strong when facing news of a cancer recurrence or situations when the progression of a disease conditions the decline of the patient."

Cynthia Mayté Villarreal Garza devotes her work towards women who suffer from breast cancer. She has two goals: to achieve early detection and to administer appropriate treatment that increases the recovery rate. In addition, she promotes initiatives that help women confront the illness in the best possible way in order to continue their lives with strength. 

Dr. Villarreal has published more than 120 papers in international journals, and is an opinion leader in breast cancer nationally and internationally.

She is the head of the Oncology Department at the Breast Cancer Center in Hospital Zambrano Hellion. Combining her medical career with her interest in research, she has taken practical action towards the care and education of her patients, with whom she establishes a close relation to provide guidance and support. She has even started an awareness project on metastatic breast cancer with the intention of encouraging assistance with services such as palliative medicine and care, nutrition, rehabilitation and psychology. 

As director of the Joven & Fuerte [Young & Strong] program, Villarreal Garza optimizes clinical care to assist both patients and their families. As head of the Alerta Rosa [Pink Alert] program for Asociación MILC (Médicos e Investigadores en la Lucha Contra el Cáncer de Mama), her goal is to reduce assistance times by classifying and prioritizing women with mammary symptoms or abnormal tests. And the Genetic Counseling Program for Breast Cancer Risk, implemented in TecSalud hospitals, has granted access to genetic testing for resource-scarce communities. 

• Ambulatory Internal Medicine
• Ambulatory Rotation
• Clinical Rotation
• Doctoral Research
• Doctoral Research Proposal
• Epidemiological Research
• Hospital Internal Medicine
• Hospital and Outpatient Clinic in Internal Medicine
• Hospitalist Rotation
• Oncology Clinic
• Oncology and Palliative Care
• Research Internship
• Research Seminar

• Clinical behavior and outcomes of breast cancer in young women with germline BRCA pathogenic variants.  npj Breast Cancer.  7. 2021
• Adjuvant endocrine therapy for premenopausal women with breast cancer: Patient adherence and physician prescribing practices in Mexico.  Breast.  59:8-15. 2021
• Breast cancer associated pathogenic variants among women 61¿years and older with triple negative breast cancer.  Journal of Geriatric Oncology.  12:749-751. 2021
• Factors associated with the desire to undergo post-mastectomy breast reconstruction in a Mexican breast cancer center.  Supportive Care in Cancer.  29:2679-2688. 2021 
• Impact of chemotherapy regimen and sequence on the effectiveness of scalp cooling for alopecia prevention.  Breast Cancer Research and Treatment.  185:453-458. 2021

More publications
 

• Doctor of Science, Universidad Nacional Autónoma de México (U.N.A.M.)
• Internal Medicine, Universidad Nacional Autónoma de México (U.N.A.M.)
• Master of Medical Sciences, Universidad Nacional Autónoma de México (U.N.A.M.)
• Surgeon, Tecnológico de Monterrey

• XXXI Premio "Miguel Aleman Valdés" en el Área de Salud, conferred by Fundación Miguel Alemán, 2017
• Susan G Komen Grant 2015. An Education Intervention Program on Breast Cancer in Young Women for Patients and Physicians, conferred by Susan G Komen Grant, 2015
• Premios Bieniales de FUNSALUD a la Investigación en Cáncer de Mama por el trabajo "Impact of diabetes and hyperglycemia on survival in advanced breast cancer patients, conferred by FUNSALUD, 2013
• 2010 ASCO Cancer Foundation Merit Award, conferred by ASCO, 2010
• 2009 ASCO International Development and Education, conferred by ASCO, 2009
• Mexican Researcher Certification - Level 2 (Villarreal-Garza, Cynthia Mayte)
   

"It is difficult to remain strong when facing news of a cancer recurrence or situations when the progression of a disease conditions the decline of the patient."

Cynthia Mayté Villarreal Garza devotes her work towards women who suffer from breast cancer. She has two goals: to achieve early detection and to administer appropriate treatment that increases the recovery rate. In addition, she promotes initiatives that help women confront the illness in the best possible way in order to continue their lives with strength. 

Dr. Villarreal has published more than 120 papers in international journals, and is an opinion leader in breast cancer nationally and internationally.

She is the head of the Oncology Department at the Breast Cancer Center in Hospital Zambrano Hellion. Combining her medical career with her interest in research, she has taken practical action towards the care and education of her patients, with whom she establishes a close relation to provide guidance and support. She has even started an awareness project on metastatic breast cancer with the intention of encouraging assistance with services such as palliative medicine and care, nutrition, rehabilitation and psychology. 

As director of the Joven & Fuerte [Young & Strong] program, Villarreal Garza optimizes clinical care to assist both patients and their families. As head of the Alerta Rosa [Pink Alert] program for Asociación MILC (Médicos e Investigadores en la Lucha Contra el Cáncer de Mama), her goal is to reduce assistance times by classifying and prioritizing women with mammary symptoms or abnormal tests. And the Genetic Counseling Program for Breast Cancer Risk, implemented in TecSalud hospitals, has granted access to genetic testing for resource-scarce communities. 

• Ambulatory Internal Medicine
• Ambulatory Rotation
• Clinical Rotation
• Doctoral Research
• Doctoral Research Proposal
• Epidemiological Research
• Hospital Internal Medicine
• Hospital and Outpatient Clinic in Internal Medicine
• Hospitalist Rotation
• Oncology Clinic
• Oncology and Palliative Care
• Research Internship
• Research Seminar

• Clinical behavior and outcomes of breast cancer in young women with germline BRCA pathogenic variants.  npj Breast Cancer.  7. 2021
• Adjuvant endocrine therapy for premenopausal women with breast cancer: Patient adherence and physician prescribing practices in Mexico.  Breast.  59:8-15. 2021
• Breast cancer associated pathogenic variants among women 61¿years and older with triple negative breast cancer.  Journal of Geriatric Oncology.  12:749-751. 2021
• Factors associated with the desire to undergo post-mastectomy breast reconstruction in a Mexican breast cancer center.  Supportive Care in Cancer.  29:2679-2688. 2021 
• Impact of chemotherapy regimen and sequence on the effectiveness of scalp cooling for alopecia prevention.  Breast Cancer Research and Treatment.  185:453-458. 2021

More publications
 

• Doctor of Science, Universidad Nacional Autónoma de México (U.N.A.M.)
• Internal Medicine, Universidad Nacional Autónoma de México (U.N.A.M.)
• Master of Medical Sciences, Universidad Nacional Autónoma de México (U.N.A.M.)
• Surgeon, Tecnológico de Monterrey

• XXXI Premio "Miguel Aleman Valdés" en el Área de Salud, conferred by Fundación Miguel Alemán, 2017
• Susan G Komen Grant 2015. An Education Intervention Program on Breast Cancer in Young Women for Patients and Physicians, conferred by Susan G Komen Grant, 2015
• Premios Bieniales de FUNSALUD a la Investigación en Cáncer de Mama por el trabajo "Impact of diabetes and hyperglycemia on survival in advanced breast cancer patients, conferred by FUNSALUD, 2013
• 2010 ASCO Cancer Foundation Merit Award, conferred by ASCO, 2010
• 2009 ASCO International Development and Education, conferred by ASCO, 2009
• Mexican Researcher Certification - Level 2 (Villarreal-Garza, Cynthia Mayte)