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Luz María Martínez Calderón

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Luz María Martínez Calderón

Research Professor at the Department of Chemistry and Nanotechnology

School of Engineering and Sciences

Campus Monterrey


Expertise

  • Chemistry and Nanotechnology

Contact

mail luzvidea@tec.mx 

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Overview

Dr. Luz María Martínez Calderón graduated with honors from Tecnológico de Monterrey with a Bachelor of Science in Chemistry and obtained her Ph.D. in Chemistry from Arizona State University. She is currently Research Professor at the Department of ​​Chemistry and Nanotechnology at the Tecnológico de Monterrey, Monterrey campus, and participates as an adjunct professor in the Department of Chemistry at Rice University.

Her research lines include: Design and construction of portable instruments for thermal and structural characterization, Preparation and characterization of micro and Nano-dispersions of thermally stable amorphous drugs to improve solubility and bioavailability of poorly soluble active principles, Evaluation of therapeutic efficiency of new pharmaceutical formulations in the form of co-amorphous and co-crystalline formulations with potential applications in the treatment of high incidence diseases (hypertension-hypercholesterolemia-diabetes) and Stabilization and thermal characterization of active principles and biomolecules with applications in the biotechnology and pharmaceutical industry.

In terms of attracting funds and research projects, Dr. Martínez has served as coordinator and head of projects such as "Estudio de las transiciones de fase e interacciones intermoleculares en sistemas binarios en función de su composición y temperatura", funded by the call of Ciencia Básica SEP-CONACyT 2016-2020, "Estudio del mecanismo de preservación de biomoléculas de través de la generación de matrices vítreas de azúcares no reductores", funded by the call of Ciencia Básica SEP-Conacyt-2008, the educational Innovation project "Construyendo nuestros instrumentos de Medición: Construcción y uso de instrumentos de caracterización térmica de materiales. Do it yourself", funded by the NOVUS 2012 call for Educational Innovation and "Optimización de procesos de preservación de biomoléculas", funded by the Zambrano-Hellion Fund.

Dr. Martínez has generated knowledge through the direction of more than 30 undergraduate and graduate thesis projects; her scientific contributions have been published in indexed journals such as Journal of Chemical Education, Thermochimica Acta, Biopolymers, Nature, International Journal of pharmaceutics, Molecules, European Journal of Pharmaceutics and Biopharmaceutics, among others. She has been a member of the steering committee of the Consejo Nacional de la Enseñanza de las Ciencias Químicas A.C. from 2011 to 2017 and is a member of the AAPS (American Association of Pharmaceutical Scientists) and the ACS (American Chemical Society).

She worked in the industrial sector developing analytical techniques to measure physicochemical properties of glass. As a result, she received recognition for her contribution to Technological Development in VITRO.

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Teaching Activities

  • Analysis of Properties and Transformation of Matter
  • Analysis of the Transformation of Matter in Chemical Processes
  • Chemical Research
  • Chemistry
  • Directed Study
  • Doctoral Defense
  • Doctoral Research
  • Foundation of the Structure and Transformation of Matter
  • Guided Research
  • Integration Project in Chemistry and Nanotechnology
  • Introduction to Chemical Research
  • Research Internship
  • Research Project in Chemistry and Nanotechnology
  • Research Proposal
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Publications

  • Nano and micro dispersions of two-phase amorphous-amorphous drug formulations as strategy to enhance solubility of pharmaceuticals. Materials Today: Proceedings 13, pp. 390-396 (2019)
  • Roles of Undergraduate Students: Trainee, Tutor and Designer" International Journal on Interactive Design and Manufacturing (IJIDeM) 13(4), pp. 1457-1467 (2019) 
  • "Highly Soluble Glimepiride and Irbesartan Co-amorphous Formulation with Potential Application in Combination Therapy" (AAPS PharmSciTech 20(4),144 1-12 (2019)
  • "Co-Amorphous Simvastatin-Nifedipine with Enhanced Solubility for Possible Use in Combination Therapy of Hypertension and Hypercholesterolemia" Molecules, 23, 2161 (2018)
  • "Two-phase amorphous-amorphous solid drug dispersion with enhanced stability, solubility and bioavailability; resulting from ultrasonic dispersion of an immiscible system" European Journal of Pharmaceutics and Biopharmaceutics, 119 243-252 (2017) 

More publications

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Education and Training

  • Doctor of Chemistry, Arizona State University
  • Bachelor of Chemical Sciences, Tecnológico de Monterrey
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Awards and Honors

  • National Award " Inspiring Profesor", for Research and Graduate (2016 y 2020)
  • MUJER-TEC-2013 (Mentoring category)
  • Distinguished Novus-Professor (distinction for profile as an innovator in education)
  • Excellence in Honors Teaching Award
  • Mexican Researcher Certification - Level 1 (Martínez-Calderón, Luz María)